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Kisspeptin

Kisspeptin-10 (Metastin 45-54)

Last updated: March 2026

Sequence

10 amino acids (active fragment)

Origin

Naturally occurring neuropeptide

Research Dose

Clinical studies use 1.6-12.8nmol/kg IV or subcutaneous. Research protocols typically use 100-500mcg subcutaneous.

Category

Hormonal Health

How It Works

Kisspeptin is a neuropeptide that acts as the master upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. It stimulates GnRH neurons in the hypothalamus, which triggers the release of LH and FSH from the pituitary. This cascade regulates sex hormone production (testosterone, estrogen). Kisspeptin-10 is the shortest active fragment commonly used in research.

Key Benefits

01

Master regulator of reproductive hormones

02

Stimulates GnRH and LH release

03

Studied for fertility treatment

04

May support natural testosterone production

Research Highlights

  • Master regulator of puberty onset and reproductive function

  • Stimulates physiological LH pulses (unlike hCG)

  • Clinical trials for IVF show improved oocyte maturation

  • Studied as an alternative trigger for egg retrieval in IVF

  • May diagnose and treat hypothalamic amenorrhea

Available Forms

  • Lyophilized powder for injection

Legal Status

Kisspeptin is available for research purposes. Used in clinical trials for fertility. Not FDA-approved as a drug. Not a controlled substance.

Price Range

$39.99 — $39.99

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Research & Education Only — The information on this page is for research and educational purposes only. It does not constitute medical advice. Consult a qualified healthcare professional before making any decisions.