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LL-37

LL-37 (Cathelicidin Antimicrobial Peptide)

Last updated: March 2026

Sequence

37 amino acids

Origin

Human cathelicidin

Research Dose

Research protocols vary widely. Typical subcutaneous doses range from 50-100mcg. Used in wound care research at various topical concentrations.

Category

Immune

How It Works

LL-37 is the only human cathelicidin antimicrobial peptide. It is part of the innate immune system, released by neutrophils, macrophages, and epithelial cells. LL-37 kills bacteria by disrupting their cell membranes, inhibits biofilm formation, modulates inflammation, and promotes wound healing through angiogenesis and cell migration.

Key Benefits

01

Broad-spectrum antimicrobial activity

02

Modulates immune response

03

May support wound healing

04

Anti-biofilm properties studied

Research Highlights

  • The only human cathelicidin antimicrobial peptide

  • Active against gram-positive and gram-negative bacteria

  • Disrupts bacterial biofilms

  • Modulates inflammatory cytokine response

  • Vitamin D upregulates natural LL-37 expression

Available Forms

  • Lyophilized powder for injection

Legal Status

LL-37 is available for research purposes. Not FDA-approved. Not a controlled substance.

Price Range

$36.00 — $89.00

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Research & Education Only — The information on this page is for research and educational purposes only. It does not constitute medical advice. Consult a qualified healthcare professional before making any decisions.